Surfski Champion Oscar Chalupsky's Body Responds to Talvey Cancer Treatment After Serious Reaction
- Decorated surfski champion Oscar Chalupsky began his last line of treatment for advanced multiple myeloma and skin cancer this week
- Chalupsky developed a serious reaction to his first dose of immunotherapy drug Talvey before his second dose yielded better results
- The 63-year-old shared a health update from Mediclinic Constantiaberg, revealing improvements across all blood markers
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Canoe and surfski legend Oscar Chalupsky has reported that his body is beginning to respond to a new immunotherapy drug after a difficult start to his latest course of cancer treatment.

Source: Instagram
Chalupsky, 63, who has been battling advanced multiple myeloma and an aggressive secondary skin cancer, began treatment with a drug called Talvey this week, marking what his doctors have described as his last available line of treatment. The former 12-time World Molokai Surfski Champion was hospitalised at Mediclinic Constantiaberg following a serious reaction to his first dose on Thursday.
His second dose, administered on Saturday, produced a more encouraging response.
Chalupsky's blood markers show improvement
Writing from his hospital bed on Facebook, Chalupsky shared a cautiously optimistic update for followers who have been tracking his health journey.
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"Everything is looking good. My bloods are not perfect, but they are on the right trajectory, and that is the most important thing," he wrote.
He added that there had been "slight improvements across all my blood markers," though he acknowledged he was not yet out of danger.
"I am not out of the woods yet, but I am moving in the right direction. My blood pressure is much better, and the Cytokine Release Syndrome is now behind me," he said.
As seen in the post below on Instagram.
Earlier in the week, Chalupsky had revealed that his blood test results were "dire," with dangerously low vitals, making the partial turnaround all the more significant.
What is Talvey and why it matters
Chalupsky was first diagnosed with multiple myeloma, a bone marrow and blood cancer, in 2019, and subsequently developed a secondary skin cancer. His treatment has involved a combination of chemotherapy, immunotherapy and radiation.
Talvey is an immunotherapy drug designed to direct the immune system to identify and destroy cancer cells. For Chalupsky, the goal of the treatment is to reduce the cancer burden in his body, slow or halt the progression of his myeloma, and extend the period during which the disease remains controlled.
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