Moderna Starts HIV Vaccine Trials in the US Using mRNA Technology, Hoping to Curb Spread

Moderna Starts HIV Vaccine Trials in the US Using mRNA Technology, Hoping to Curb Spread

  • Moderna and the International AIDS Vaccine Initiative has started the first phase of clinical trials for an HIV vaccine in the US
  • 56 HIV negative, healthy adults are participating in the HIV vaccine trial, and eight will only receive a booster shot
  • The Moderna HIV vaccine uses mRNA technology to trigger antibody production by the immune system

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WASHINGTON DC - The International AIDS Vaccine Initiative and Moderna, a biotech and pharmaceutical company, announced that clinical trials for an HIV vaccine have started in the US.

The first phase of the trial consists of 56 HIV negative and healthy adults. The vaccine uses mRNA technology, similar to that of Covid-19 vaccines and will produce bnAbs (broadly neutralising antibodies).

These antibodies will protect against HIV and its many variants, eNCA reports. Vaccinated people's bodies will produce the bnAbs through their B lymphocytes in their immune system.

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Moderna, vaccine, HIV, AIDS, HIV vaccine, antibodies, mRNA technology, immune system, health news
Moderna's HIV vaccine could dramatically decrease the number of infections. Image: Getty Images
Source: Getty Images

The aim of the HIV vaccine

According to ABC News, an estimated 38 million people globally are infected with HIV. While treatments and medications have been developed to help HIV positive people lead reasonably normal lives, this is the first time a vaccine has been developed.

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Moderna has developed a vaccine and a booster shot, although it is not clear at this stage how often one would need to get a booster. Eight of the trial participants will receive just a booster and no vaccine to help ascertain its efficacy.

The trial will take place in three different American cities; namely Seattle, Atlanta and San Antonio. Dr Mark Feinberg, the CEO and president of the International AIDS Vaccine Initiative, said that he and his team are hopeful that the first trial of the HIV vaccine will be a success.

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Reactions to HIV vaccine trial

@Americanhope78 said:

"Wow if that works can you believe how many critics mRNA vaccines they would silence."

@TheTruth_quest remarked:

"Not interested! Don’t trust them after they “botched” the Covid jab!"

@ZealousWind asked:

@JAndrewLyon1 shared:

"So cool. Just thinking how far they can go if they become motivated by conscience and not money! Because their COVID vaccine probably saved more than just my life. Please don't hesitate to get vaccinated. But it's your own life and your own choice!"

@AyoDMak believes:

"It was bound to happen, the technology is there."

@loss_leader_ said:

20 Years on: Government ordered to supply HIV drugs to pregnant women

In other news about HIV, Briefly News previously reported that it has been 20 years since the Pretoria High Court ruled that Government would have to provide nevirapine to all pregnant women to stop the transmission of HIV to their babies.

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The ruling stated that the government would have to allow the drug to be available to women who used public hospitals to give birth. The government was also informed that it would have to introduce and institute a programme to reduce transmission of the virus from mother to child across the country.

While sexual intercourse is considered the primary method of HIV transmission, the virus is still passed to children through their mothers. The most common way this happens is through delivery as the baby comes into direct contact with its mothers' blood.

Source: Briefly News

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